‡ In these countries please contact our distributor

PICO in DFUs and VLUs

Not intended for healthcare professionals in the US.

Challenging hard-to-heal wounds

PICO sNPWT evidence shows significantly improved healingi-iv in diabetic foot ulcers and venous leg ulcers, compared to tNPWT1

A recent multisite RCT compared our PICO Single Use Negative Pressure Wound Therapy System  (sNPWT) to traditional NPWT (tNPWT) for the treatment of diabetic foot ulcers (DFUs) and venous leg ulcers (VLUs), with some compelling results.

PICO sNPWT demonstrated, over 12 weeks from baseline, compared to tNPWTi:

  39.1% relative reduction in wound areaii1.
  32.5% relative reduction in wound depthiii1.
  91.1% relative reduction in wound volumeiv1.
  51% more wounds were closed at 12 weeksv1.


Why settle for tNPWT when you may achieve significantly better wound healing with PICO sNPWTi-v1?

Download the study summary.


Watch an animation of the study


Challenge your standard care, for improved patient satisfaction and efficiencies1,2

Whilst improving wound healing and closure1, PICO sNPWT demonstrated a dressing wear time 3.4 days longer1 than tNPWT, with a significant improvement in overall patient satisfactionvi for:

- Willingness to use againvii2
- Comfort of useviii2
- Impact on mobilityix2
- Impact on activity levelsx2
- Impact on sleepxi2

Rosemary Hill

Kevin and Roxanne Price

Arrange for a Smith & Nephew representative to contact you to discuss how our new PICO 14 sNPWT System could help your staff and patients.

PICO sNPWT  - designed to be different

Unique technology found only in our PICO sNPWT has demonstrated clinical efficacy for chronic wounds and closed surgical incisions1,3.

- AIRLOCK Technology delivers evenly distributed negative pressure across the dressing to ensure delivery of NPWT to the entire wound, for up to 7 days4.
- Designed to help minimize pain and trauma on application and removal5.
- Optimal fluid management to help reduce maceration6.
- Up to 99.9% of bacteria is locked away from the wound once absorbed into the dressing7.


For effective, easy-to-use traditional negative pressure wound therapy (tNPWT)

The RENASYS™ tNPWT system addresses the clinical need for traditional negative pressure wound therapy across a wide range of acute, chronic and surgical wound types.


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For detailed product information, including indications for use, contraindications, effects, precautions, warnings, and important safety information, please consult product’s Instructions for Use (IFU) prior to use.


i) 164 patients with lower extremity ulcers for more than 4 weeks. 104 with VLUs (2-36cm2), 60 with DFUs (0.5-10cm2). 63.4% male and 36.6% female, with a mean age of 61.5 years.
ii) Wound area: p<0.001 (VLUs: p=0.007, DFUs: p=0.031)
iii) Wound depth: p<0.014
iv) Wound volume: p<0.013
v) Wound closure: p=0.002
vi) Overall patient satisfaction: p=0.006
vii) Willingness to use again: p=0.003
viii) Comfort of use: p<0.001
ix) Impact on mobility: p<0.001
x) Impact on activity levels: p=0.017
xi) Impact on sleep: p=0.017



1) Kirsner R, Dove C, Reyzelman A, Vayser D, Jaimes H. A prospective, randomized, controlled clinical trial on the efficacy of a single-use negative pressure wound therapy system, compared to traditional negative pressure wound therapy in the treatment of chronic ulcers of the lower extremities. Wound Rep Regen, 2019. DOI: 10.1111/wrr.12727
2) Kirsner R, Dove C, Reyzelman A, Vayser D, Jaimes H. Randomized controlled trial on the efficacy and acceptance of a single-use negative pressure wound therapy system versus traditional negative pressure wound therapy in the treatment of lower limb chronic ulcers (VLU and DFU). Poster presented at the 10th Annual Abu Dhabi Wound Care Conference, March 23–24, 2019. Abu Dhabi, United Arab Emirates.
3) Strugala V and Martin R. Meta-analysis of comparative trials evaluating a prophylactic single-use negative pressure wound therapy system for the prevention of surgical site complications. Surgical Infections Vol 18 Number 07 (2017). DOI: 10.1089/sur.2017.156. 810-819.
4) Data on file. DS/17/253/R version2. Project Opal PICO 7 system stability testing, initial time point. November 2017.
5) Loveluck J et al. Biomechanical modelling of forces applied to closed incision during single-use negative pressure wound therapy. Eplasty 2016; 16e20.
6) Malmsjö M et al. Biological effects of a disposable, canisterless Negative Pressure Wound Therapy system. Eplasty 2014; 14:e15.
7) Data on file report 1712012. The retention of P.aeruginosa and S. aureus bacteria within PICO dressings after 72 hours under NPWT in a dynamic model. December 2017.
8) Dowsett C, et al. Use of PICO_ to improve clinical and economic outcomes in hard-to-heal wounds. Wounds International. 2017;8, p53–58
9) Joy, H et al. A collaborative project to enhance efficiency through dressing change practice. Journal of Wound Care 2015;24(7):312,314-7

NICE recognition for PICO

Read the NICE guidelines, recommending the adoption of PICO sNPWT
to help reduce surgical site complications in high-risk patients.

Read the guidelines

Helping you get
surgical site complications

Find out how PICO◊  can help