New publication backs incisional NPWT
Discover up-to-date meta-analysis and TSA results from an independent peer review on the efficacy of NPWT vs. standard dressings for SSI incidence, including 57 RCTs with 13,744 patients.1
+ The Lancet™ publication
"Incisional negative pressure wound therapy for the prevention of surgical site infection: an up-to date meta-analysis and trial sequential analysis."
+ Overview
- Previously conducted meta-analyses and RCTs for NPWT prevention of SSI are contradictory.
- Implementation of NPWT is impaired due to inconsistent recommendations by international guidelines.
- This study compared NPWT with standard dressings on closed incisional wounds in adult patients undergoing any type of surgery.
- Providing an up-to date systematic review and meta-analysis.
+ Methodology
+ Results
+ Conclusion
This meta-analysis confidently showed that single use iNPWT reduces SSI irrespective of surgical specialty, whilst trial sequential analysis demonstrated the robustness of this evidence. Additionally, no significant differences were observed between -80mmHg and -125mmHg devices.
+ Our engagement
We are dedicated to supporting healthcare professionals in reducing the human and economic impacts of post-operative surgical site complications (SSCs).
The development of SSCs, such as surgical site infections (SSIs), oedema, seroma, haemotoma, or surgical wound dehiscence is a substantial burden for patients and healthcare systems globally.2
Discover how we are shaping what's possible in reducing the burden of surgical wound complications
References
™ The Lancet is a trademark of Elsevier Limited
- Groenen H, et al. The Lancet Journal. Volume 62, August 2023, p1-14.
- Gillespie BM et al. Worldwide incidence of surgical site infections in general surgical patients: A systematic review and meta-analysis of 488,594 patients. Int J Surg. 2021 Nov;95:106136. doi: 10.1016/j.ijsu.2021.106136. Epub 2021 Oct 13. PMID: 34655800.